Synopsis
A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
Movie Information
- Director
- Bobby Farrelly
- Writers
- Marc Hyman
- Release Year
- 2001
- Runtime
- 95 minutes
- Genre
- Action, Adventure, Animation, Comedy, Family, Science Fiction
- Language
- EN
- Country
- United States of America
- Status
- Released
- Rating
- 6.5 / 10 (1,111 votes)
Top Cast
Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
David Hyde Pierce
Drix (voice)
Brandy Norwood
Leah (voice)
Elena Franklin
Shane Detorre
Bill Murray
Frank Detorre
William Shatner
Mayor Phlegmming (voice)
Ron Howard
Tom Colonic (voice)
Official Trailer
Ready to watch Osmosis Jones?
Pick a streaming source and press play — free, HD, no signup.
▶ Watch Osmosis Jones FreeSimilar Movies
Retrograde
2004 ★ 3.1
Lilies of the Field
1963 ★ 7.2
One Shivery Night
1950 ★ 10.0
Cold Sweat
1970 ★ 5.7
Thin Ice
2012 ★ 6.5
Outrageous Big Machines
2008
The Hole
1998 ★ 7.0
Taro the Dragon Boy
1979 ★ 6.4
Airborne
1998 ★ 3.3
Scott of the Antarctic
1948 ★ 7.2
Ice Twister
2026
Virus
1980 ★ 6.3
Riff-Raff
1991 ★ 6.7
Mind Leech
2023 ★ 7.0
You May Also Like
LEGO DC Comics Super Heroes: The Flash
2018 ★ 6.9
Chickenhare and the Hamster of Darkness
2022 ★ 7.2
Ralph Breaks the Internet
2018 ★ 7.2
LEGO Marvel Avengers: Mission Demolition
2024 ★ 6.5
The Willoughbys
2020 ★ 7.0
Invader Zim: Enter the Florpus
2019 ★ 7.4
Phineas and Ferb: Star Wars
2014 ★ 7.1
Phineas and Ferb: Mission Marvel
2013 ★ 6.5
Batman: Return of the Caped Crusaders
2016 ★ 6.5
Regular Show: The Movie
2015 ★ 7.9
Jimmy Timmy Power Hour
2004 ★ 7.0
The Batman/Superman Movie: World's Finest
1997 ★ 7.4
Leroy & Stitch
2006 ★ 6.5
Shorts
2009 ★ 5.9
More Action Movies
Spider-Man: Brand New Day
2026 ★ 7.9
The Odyssey
2026 ★ 8.0
Colony
2026 ★ 8.1
Facing El Chapo
2026 ★ 8.8
Spider-Man: No Way Home
2021 ★ 7.9
Supergirl
2026 ★ 6.7
The Avengers
2012 ★ 8.1
Avengers: Infinity War
2018 ★ 8.2
The Mandalorian and Grogu
2026 ★ 7.5
Demon Slayer: Kimetsu no Yaiba Infinity Castle
2025 ★ 8.8
Masters of the Universe
2026 ★ 7.2
The Shadow's Edge
2025 ★ 8.2
Spider-Man: Across the Spider-Verse
2023 ★ 8.3
The Odyssey
2026 ★ 4.0
More with Chris Rock
Grown Ups
2010 ★ 6.4
PAW Patrol: The Mighty Movie
2023 ★ 6.9
Madagascar
2005 ★ 6.9
A.I. Artificial Intelligence
2001 ★ 7.1
Madagascar: Escape 2 Africa
2008 ★ 6.5
Madagascar 3: Europe's Most Wanted
2012 ★ 6.6
Bee Movie
2007 ★ 6.1
Grown Ups 2
2013 ★ 6.2
Lethal Weapon 4
1998 ★ 6.6
Spiral: From the Book of Saw
2021 ★ 5.9
Roald Dahl's The Witches
2020 ★ 6.3
You Don't Mess with the Zohan
2008 ★ 5.7
Bad Company
2002 ★ 5.5
The Longest Yard
2005 ★ 6.7
More from Bobby Farrelly
Dumb and Dumber
1994 ★ 6.7
There's Something About Mary
1998 ★ 6.6
Me, Myself & Irene
2000 ★ 6.6
Dumb and Dumber To
2014 ★ 5.6
Shallow Hal
2001 ★ 6.2
Hall Pass
2011 ★ 5.8
The Heartbreak Kid
2007 ★ 5.8
Kingpin
1996 ★ 6.5
Dumb and Dumberer: When Harry Met Lloyd
2003 ★ 4.2
Fever Pitch
2005 ★ 6.2
Stuck on You
2003 ★ 5.4
The Three Stooges
2012 ★ 5.8
Dear Santa
2024 ★ 6.2
Champions
2023 ★ 6.7
Trending Now
Mayday
2026 ★ 7.6
The Runner
2026 ★ 6.5
Obsession
2026 ★ 8.2
Coyote vs. Acme
2026 ★ 7.6
The Whisper Man
2026 ★ 6.8
Backrooms
2026 ★ 7.1
Toy Story 5
2026 ★ 8.3
Buddy
2026 ★ 8.3
Clash of the Thundermans
2026 ★ 6.8
Project Hail Mary
2026 ★ 8.6
Mutiny
2026 ★ 6.4
Batman: Knightfall Part 1: Knightfall
2026 ★ 9.1
Minions & Monsters
2026 ★ 7.6
I Want Your Sex
2026 ★ 6.1
Popular This Week
Explore related titles
Frequently Asked Questions
Where can I watch Osmosis Jones online for free?
You can watch Osmosis Jones (2001) online for free in HD on FreeFlix. No signup or subscription is required — just open this page and click play.
Is Osmosis Jones available in HD?
Yes. FreeFlix offers Osmosis Jones in full HD with multiple mirror sources, so if one source is slow you can switch in one click.
What is Osmosis Jones about?
A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
Do I need to register or pay?
No. FreeFlix is completely free, with no registration, account, credit card, or hidden charges.